Research and development in the field of Marine Biotechnology
Marine microorganisms are a prolific resource of new technical enzymes and pharmacologically active agents or lead structures. Their special living conditions and functions in the ecosystem force them to produce a vast number of enzymes with unique activities and bioactive metabolites with new structures.
Main Topics
Bioactive compounds
- Screening and characterisation of cyanobacteria and marine fungi producing substances with antibacterial, antifungal, antiviral, cytostatic, immunomodulatory or enzyme inhibitory properties
- Isolation, structure elucidation and analysis of bioactive compounds
- cultivation of marine microorganisms
- Target analyses (Proteomics)
Cold-adapted enzymes
- Screening of psychrophilic microorganisms with cold-adapted enzymatic activities
- Cloning and expression of cold-adapted enzymes
Enzyme production processes
- Development of bacterial expression systems for the overproduction of thermolabile or insoluble enzymes
- Optimisation of bacterial fermentation processes
- Quality control of recombinant enzymes by proteomics